Prostate-specific antigen (PSA) test detects the amount of this enzyme made by the prostate gland of adult men. Small amounts of prostate-specific antigen (PSA) are normally released into the bloodstream. When the prostate is enlarged, infected, or diseased, larger amounts of PSA are released. Men with prostate cancer MAY have high levels of PSA.
The American Cancer Society recommends that men 50 years of age and older be screened annually for prostate cancer with both a digital rectal examination (DRE) and a PSA blood test. Men in high-risk groups, such as African-Americans, or those with a strong family history of prostate cancer, should consider being tested at 45 years of age.