Specialty medical injectable medication program, requirement and policy updates August 2026

Review the following tables to determine changes to our specialty medical injectable medication programs and drug policy updates for August 2026.

Review the following tables for changes to our specialty medical injectable medication programs and drug policy updates.

Review at Launch

The following specialty medical injectable medications have been added to Review at Launch for UnitedHealthcare commercial business:

Medication Name

HCPCS Code(s)

Ranluspec®
(ranibizumab-hkdz)
Biosimilar to Lucentis®
J3490/J3590/C9399
Lumvoa™
(veligrotug-vvze)
J3490/J3590/C9399

Updates to drug program requirements and drug policies

Effective Sept. 1, 2026, the following drug program requirements and drug policy updates will be made for UnitedHealthcare commercial business:

Medication NameHCPC(s)Summary of Changes
Armlupeg™
(pegfilgrastim-unne)
Biosimilar to Neulasta®

Q5169

  • Add as non-preferred product
Aukelso™
(denosumab-kyqq)
Biosimilar to Xgeva®

Q5161

  • Add as non-preferred product for all oncology indications
Bilprevda®
(denosumab-nxxp)
Biosimilar to Xgeva

Q5162

  • Add as preferred product for all oncology indications
Khapzory®
(levoleucovorin)

J0642

  • Add as non-preferred product for all oncology indications
Levoleucovorin

J0641

  • Add as preferred product for all oncology indications
Lutrate® Depot
(leuprolide acetate)

J1954

  • Add as non-preferred product for all oncology indications
Phesgo®
(pertuzumab, trastuzumab, and hyaluronidase-zzxf)

J9316

  • Remove from Site of Care
Vykoura™
(leucovorin)

J3490/J3590/C9399

  • Add as non-preferred product for all oncology indications
Xtrenbo™
(denosumab-qbde)
Biosimilar to Xgeva
Q5167
  • Add as preferred product for all oncology indications
Xbryk™
(denosumab-dssb)
Biosimilar to Xgeva
J3490/J3590/C9399
  • Add as non-preferred product for all oncology indications

UnitedHealthcare will honor all approved prior authorizations on file until the end date on the authorization or the date the member’s eligibility changes. Upon prior authorization renewal, the updated policy will apply.

Note: Certain specialty medical injectable programs and updates may not be implemented for some providers or commercial members where prohibited by applicable state insurance mandates or regulations. Providers are encouraged to confirm whether prior authorization or other program requirements apply.

For questions, please contact your broker or UnitedHealthcare representative.

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